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B virus infection

B virus infection

5 April 2024

Causative agent

B virus (also known as herpes simiae virus) is a type of herpes virus that is usually found among macaques, a type of wild monkeys commonly found in Hong Kong. B virus is naturally carried in the saliva, urine and stool of macaques. Most infected macaques are usually asymptomatic or having mild disease.

Human infection of B virus is rare, with about 50 people documented to have been infected globally since 1932. Human infection has been reported in United States, Canada, Mainland China and Japan, and were mainly caused by bites or scratches by monkeys.

Clinical features

Infected persons may initially present with flu-like symptoms, such as fever and chills, muscle ache, fatigue and headache. Vesicular skin lesions may then occur at the bite or scratch site. As disease progresses, the virus can spread to the central nervous system resulting in pain/numbness/itchiness near the wound, problems with muscle coordination, damage to the nervous system and even death.

Mode of transmission

Human infections are mainly caused by bites or scratches by infected monkeys, while human-to-human transmissions are very rare.

Incubation period

Symptoms usually occur within 1 month of the patient being exposed.

Management

Human infection requires professional medical management.

Prevention

To minimise risk of acquiring B virus, members of the public are advised to note the following:

  1. Stay away from wild monkeys and avoid touching or feeding them;
  2. In case there are wounds caused by monkeys, wash the wound with a plenty of running water and seek medical attention immediately.

Members of the public may also visit website of the Agriculture, Fisheries and Conservation Department for more information on do's and don'ts when encountering monkeys: www.afcd.gov.hk/english/conservation/con_fau/con_fau_nui/con_fau_nui_str/con_fau_nui_str.html