Dengue fever is an acute mosquito-borne infection caused by the dengue viruses. This is found in tropical and sub-tropical regions around the world. For instance, dengue fever is an endemic illness in many countries in South East Asia. The dengue viruses encompass four different serotypes, each of which can lead to dengue fever and severe dengue (also known as 'dengue haemorrhagic fever').
Dengue fever is clinically characterised by high fever, severe headache, pain behind the eyes, muscle and joint pain, nausea, vomiting, swollen lymph nodes and rash. Some infected people may not develop apparent symptoms, and some may only have mild symptoms like fever, e.g. young children may exhibit a milder non-specific febrile illness with rash.
The symptoms of first infection are usually mild. Once recovered, lifelong immunity to that serotype of dengue virus will develop. However, cross-immunity to the other three serotypes after recovery is only partial and temporary. Subsequent infections with other serotypes of dengue virus are more likely to result in severe dengue.
Severe dengue is a severe and potentially fatal complication of dengue fever. Initially, the features include high fever, which lasts for 2 – 7 days and can be as high as 40 – 41°C, facial flush and other non-specific constitutional symptoms of dengue fever. Later, there may be warning signs such as severe abdominal pain, persistent vomiting, rapid breathing, fatigue, restlessness and manifestations of bleeding tendency such as skin bruises, nose or gum bleeding, and possibly internal bleeding. In severe cases, it may progress to circulatory failure, shock and death.
Mode of transmission
Dengue fever is transmitted to humans through the bites of infective female Aedes mosquitoes. When a patient suffering from dengue fever is bitten by a vector mosquito, the mosquito is infected and it may spread the disease by biting other people. The disease cannot be spread directly from human to human. In Hong Kong, the principal vector Aedes aegypti is not found, but Aedes albopictus, which can also spread the disease, is a mosquito commonly found in Hong Kong.
The incubation period ranges from 3 – 14 days, commonly 4 – 7 days.
There is no specific treatment for dengue fever and severe dengue. Dengue fever is mostly self-limiting. Symptomatic treatment is given to relieve discomfort. Patients with severe dengue should be treated promptly with supportive management. The mainstay of treatment is to maintain the circulating fluid volume. With appropriate and timely treatment, mortality rate is less than 1%.
At present, there is no locally registered dengue vaccine available in Hong Kong. The best preventive measure in Hong Kong is to eliminate pockets of stagnant water that serve as breeding sites for mosquitoes, and to avoid mosquito bites.
General measures on preventing mosquito-borne diseases
Help prevent mosquito proliferation
Pregnant women and children of 6 months or older can use DEET-containing insect repellent. For children who travel to countries or areas where mosquito-borne diseases are endemic or epidemic and where exposure is likely, children aged 2 months or above can use DEET-containing insect repellents with a concentration of DEET up to 30%. For details about the use of insect repellents and the key points to be observed, please refer to 'Tips for using insect repellents'.
For more information about control and prevention of mosquito breeding, please visit the website of the Food and Environmental Hygiene Department (FEHD) at http://www.fehd.gov.hk/english/pestcontrol/handbook_prev_mos_breeding.html
For details, please refer to the thematic webpage of Dengue Fever.
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