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Antiviral susceptibility testing of influenza viruses in 2026

Antiviral susceptibility testing of influenza viruses in 2026

The information intends to provide a profile on the proportion of strains with reduced antiviral susceptibility. The date refers to specimen reception by the laboratory. Numbers and trends presented here should be interpreted in light of the small specimen numbers in particular categories.

Antiviral susceptibility testing of influenza A(H1)pdm09 viruses in 2026

Month No. of virus isolates tested Reduced susceptibility to oseltamivir* Reduced susceptibility to baloxavir# No. of positive samples tested H275Y substitution
No. % No. % No. %
Jan 3 1 33% 0 0% 26 0 0%
Feb 2 0 0% 0 0% 28 0 0%
Mar 6 0 0% 0 0% 50 0 0%
Apr 6 0 0% 0 0% 49 0 0%
May 4 0 0% 0 0% 51 0 0%
Jun 9 0 0% 0 0% 91 0 0%
Jul 90 0 0%
Aug
Sep
Oct
Nov
Dec

 

Antiviral susceptibility testing of influenza A(H3) viruses in 2026

Month No. of virus isolates tested Reduced susceptibility to oseltamivir* Reduced susceptibility to baloxavir#
No. % No. %
Jan 16 0 0% 0 0%
Feb 13 0 0% 0 0%
Mar 8 0 0% 0 0%
Apr 8 0 0% 0 0%
May 9 0 0% 0 0%
Jun 27 0 0% 0 0%
Jul
Aug
Sep
Oct
Nov
Dec
 

Antiviral susceptibility testing of influenza B viruses in 2026

Month No. of virus isolates tested Reduced susceptibility to oseltamivir* Reduced susceptibility to baloxavir#
No. % No. %
Jan 2 0 0% 0 0%
Feb 6 0 0% 0 0%
Mar 7 0 0% 0 0%
Apr 6 0 0% 0 0%
May 7 0 0% 0 0%
Jun 4 0 0% 0 0%
Jul
Aug
Sep
Oct
Nov
Dec

* Since May 2026, a sequencing-first approach is adopted and phenotypic assay is used to confirm cases with neuraminidase (NA) amino acid substitutions associated with reduced susceptibility to antivirals.
# By genotypic characterization.