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Bacterial pathogen isolation and percentage of antimicrobial resistance, out-patient setting

Bacterial pathogen isolation and percentage of antimicrobial resistance, out-patient setting

The presented figures refer to specimens received during the designated year.

Throat swab specimens
Organism Drugs 2020 2021 2022 2023 2024 2025
Beta-haemolytic streptococci of Lancefield Group A, C & G Penicillin 0 (0.0%) 0 (0.0%) 0 (0.0%) 0 (0.0%) 0 (0.0%) 0 (0.0%)
Erythromycin 10 (55.6%) 3 (50.0%) 1 (33.3%) 2 (100.0%) 15 (53.6%) 10 (55.6%)
No. 18 6 3 2 28 18

 

Sputum specimens
Organism Drugs /
Resistance phenotype
2020 2021 2022 2023 2024 2025
Streptococcus pneumoniae Penicillin 13 (21.7%) 5 (21.7%) 1 (12.5%) (23.8%) (29.2%) 21 (25.3%)
Erythromycin 53 (88.3%) 18 (78.3%) 7 (87.5%) 15 (71.4%) 18 (75.0%) 66 (79.5%)
Levofloxacin (1.7%) (0.0%) (0.0%) (0.0%) (4.2%) 1 (1.2%)
No. 60 23 8 21 24 83
Haemophilus influenzae Ampicillin 162 (48.6%) 91 (51.4%) 44 (67.7%) 221 (58.9%) 893 (65.9%) 468 (63.9%)
Amoxicillin + clavulanic acid 56 (16.8%) 27 (15.3%) 23 (35.4%) 83 (22.1%) 351 (25.9%) 165 (22.5%)
No. 333 177 65 375 1355 732
Moraxella catarrhalis BL+ 224 (100.0%) 36 (97.3%) 12 (100.0%) 217 (98.6%) 759 (99.7%) 1088 (99.7%)
No. 224 37 12 220 761 1091

 

Urine specimens
Organism Drugs /
Resistance phenotype
2020 2021 2022 2023 2024 2025
Escherichia coli Ampicillin 4134 (64.2%) 4818 (63.8%) 3812 (63.0%) 5321 (62.4%) 5764 (67.2%) 5406 (66.2%)
Amoxicillin + clavulanic acid 359 (5.6%) 432 (5.7%) 374 (6.2%) 555 (6.5%) 491 (5.7%) 492 (6.0%)
Nitrofurantoin 68 (1.1%) 70 (0.9%) 65 (1.1%) 67 (0.8%) 53 (0.6%) 51 (0.6%)
Co-trimoxazole 2036 (31.6%) 2291 (30.3%) 1795 (29.7%) 2463 (28.9%) 2763 (32.2%) 2573 (31.5%)
Levofloxacin 2218 (34.4%) 2689 (35.6%) 2121 (35.0%) 3084 (36.1%) 3165 (36.9%) 3038 (37.2%)
ESBL+ 1093 (17.0%) 1283 (17.0%) 1002 (16.6%) 1121 (13.1%) 1445 (16.9%) 1442 (17.6%)
Imipenem (0.09%) 14 (0.19%)# 10 (0.17%) 22 (0.26%) 33 (0.38%) 35 (0.43%)
KPC+ 0 0 0 0 0 0
NDM+ 6 12 9 22 33 34
OXA-48-like+ 0 1 1 0 0 1
No. 6444 7550 6053 8533 8575 8171
Klebsiella pneumoniae complex* Amoxicillin + clavulanic acid 109 (8.3%) 131 (9.2%) 82 (6.6%) 140 (6.6%) 132 (8.1%) 104 (6.9%)
Nitrofurantoin 339 (25.9%) 446 (31.2%) 331 (26.6%) 436 (20.6%) 257 (15.7%) 124 (8.2%)
Co-trimoxazole 225 (17.2%) 234 (16.4%) 169 (13.6%) 247 (11.7%) 248 (15.2%) 235 (15.6%)
Levofloxacin 134 (10.3%) 179 (12.5%) 110 (8.8%) 147 (6.9%) 174 (10.6%) 120 (8.0%)
ESBL+ 94 (7.2%) 143 (10.0%) 134 (10.8%) 109 (5.1%) 148 (9.1%) 120 (8.0%)
Imipenem (0.08%) (0.07%) (0.16%) (0.09%) (0.37%) (0.20%)
KPC+ 0 0 0 0 1 0
NDM+ 1 1 2 1 2 2
OXA-48-like+ 0 0 0 1 3 1
No. 1307 1429 1244 2118 1635 1508
Proteus mirabilis^ Ampicillin 294 (38.9%) 324 (38.9%) 320 (43.8%) 464 (42.3%) 556 (41.5%) 644 (45.6%)
Amoxicillin + clavulanic acid 86 (11.4%) 101 (12.1%) 102 (14.0%) 117 (10.7%) 135 (10.1%) 193 (13.7%)
Co-trimoxazole 294 (38.9%) 328 (39.4%) 297 (40.6%) 383 (34.9%) 482 (36.0%) 582 (41.2%)
Levofloxacin 129 (17.1%) 157 (18.9%) 173 (23.7%) 184 (16.8%) 301 (22.5%) 290 (20.6%)
No. 755 832 731 1098 1339 1411

 

Enteric specimens
Organism Drugs 2020 2021 2022 2023 2024 2025
Campylobacter spp. Erythromycin (13.8%) 13 (37.1%) (33.3%) (11.1%) (17.2%) (16.1%)
No. 29 35 18 27 29 31
Salmonella spp. Ampicillin 51 (67.1%) 36 (56.3%) 24 (53.3%) 22 (44.0%) 40 (58.0%) 48 (66.7%)
Co-trimoxazole 19 (25.0%) 12 (18.8%) 11 (24.4%) 12 (24.0%) 10 (14.5%) 14 (19.4%)
Ciprofloxacin (7.9%) (0.0%) (2.2%) (2.0%) (5.8%) (4.2%)
No. 76 64 45 50 69 72
Shigella spp. Ampicillin - - - - (33.3%) -
Ciprofloxacin - - - - (0.0%) -
No. 0 0 0 0 3 0
Vibrio spp. Tetracycline (0.0%) (4.4%) (5.4%) (3.7%) (0.0%) (0.0%)
No. 53 45 37 27 10 12

 

Soft tissue specimens
Organism Drugs 2020 2021 2022 2023 2024 2025
Staphylococcus aureus Oxacillin
[MRSA]
304 (29.4%) 223 (25.5%) 159 (24.1%) 175 (26.8%) 180 (24.0%) 247 (26.8%)
No. 1033 875 661 652 750 920


Abbreviations:
MRSA = methicillin-resistant Staphylococcus aureus
BL+ = beta-lactamase positive
ESBL+ = extended-spectrum beta-lactamase positive
Klebsiella pneumoniae complex is 100% resistant to ampicillin.
^ Proteus mirabilis is 100% resistant to nitrofurantoin.
# one isolate was negative for the CPE genes tested.